本科介紹 醫療服務 醫師陣容 醫療常識 教學計畫 衛教園地 門診時間 相關連結

  李美月 主任
  辛錫璋 主治醫師
  蕭璧容 主治醫師
  林昆德 大同主治醫師
  洪薇雯 主治醫師
  姜和均 主治醫師
  李宇力 大同主治醫師
  徐瑋壕 小港主治醫師
  顏詩容 大同主治醫師
  賴嘉緯 小港主治醫師
  溫緯倫 總醫師
  許乃薇 總醫師
  陳綺雯 護理長
  曾錦瑋 糖尿病衛教師
  蘇淑萍 糖尿病衛教師
  梁綉鈴 糖尿病衛教師
  林秀珠 糖尿病衛教師
  黃汝鳳 糖尿病衛教師
  林碧珍 醫檢師
  趙冠雲 秘書

 ◆辛錫璋 主治醫師
  科  別:  內分泌新陳代謝內科
現  任:  
高雄醫學大學醫學院教授
                           
高雄醫學大學附設醫院內分泌內科主治醫師

學  歷:  
高雄醫學大學醫學院醫學系
       
高雄醫學大學醫學院醫學研究所博士
       
國立神戶大學第二內科
專  長:  
糖尿病、高脂血症、甲狀腺及其他內分泌疾病 、肥胖、
                            骨質鬆弛症

經  歷:

服務機關

服務部門 / 系所

職 稱

起訖年月

現職:高雄醫學大學醫學院

醫學系

教授

1998/8 ∼迄今

   高雄醫學大學附設醫院

內分泌新陳代謝內科

主治醫師

1984/8 ∼迄今

經歷:高雄醫學大學 脂質暨醣醫學研究中心
主任
2014/8 ∼2015/7
   高雄醫學大學 醫學院
副院長
2009/8 ∼2012/7
   高雄醫學大學附設醫院 內分泌新陳代謝內科
主任
2005/8 ∼2011/7

   高雄醫學大學

研究發展處

研發長

2012/8 ∼2014/7
2004/8
2006/7

   高雄醫學大學醫學院

醫學遺傳研究所

所長

2004/8 2005/7

   高雄醫學大學醫學院

醫學研究所

所長

2000/8 2004/7

   高雄醫學大學附設醫院

內分泌新陳代謝內科

主任

1997/8 2004/7

   高雄醫學大學醫學院

醫學研究所博士班

主任

2000/8 2004/7

   高雄醫學大學附設醫院

臨床醫學研究部

部主任

2000/8 2002/7

   日本國立神戶大學

第二內科

研究員

1986/10 1987/12

   
專科執照與學會 台灣內科醫學會專科醫師
中華民國內分泌糖尿病醫學會專科醫師
中華民國糖尿病醫學會會員、常務理事
中華民國內分泌醫學會會員
台灣腎臟醫學會專科醫師
台灣腎臟醫學會會員

中華民國糖尿病衛教學會專科醫師
中華民國糖尿病衛教學會會員
、理事
研究成果目錄:

(A) 期刊論文(2010-2017)

  1. Lin HY, Lee YL, Lin KD, Chiu YW, Shin SJ, Hwang SJ, Chen HC, Hung CC. Association of Renal Elasticity and Renal Function Progression in Patients with Chronic Kidney Disease Evaluated by Real-Time Ultrasound Elastography. Sci Rep. 2017 Feb 27;7:43303.
  2. Chung HF, Al Mamun A, Huang MC, Long KZ, Huang YF, Shin SJ, Hwang SJ, Hsu CC.  Obesity, weight change, and chronic kidney disease in patients with Type 2 diabetes mellitus: a longitudinal study in Taiwan. J Diabetes. 2016 Dec 15. doi: 10.1111/1753-0407.12514. [Epub ahead of print]
  3. Wang RH, Hsu HC, Kao CC, Yang YM, Lee YJ, Shin SJ. Associations of changes in psychosocial factors and their interactions with diabetes distress in patients with type 2 diabetes: a longitudinal study. J Adv Nurs. 2016 Nov 11. doi: 10.1111/jan.13201. [Epub ahead of print]
  4. Lin KD, Shin SJ*. Reply to 'Risk reduction of Parkinson disease by statin therapy in patients with diabetes' by T. Kawada. Ann Neurol. 2017 Jan;81(1):157-158.
  5. Huang MC, Hung CH, Yu CY, Berry DC, Shin SJ, Hsu YY. The Effectiveness of Multimedia Education for Patients with Type 2 Diabetes Mellitus. J Adv Nurs. 2017 Apr;73(4):943-954.
  6. Lee MY, Tsai KB, Hsu JH, Shin SJ, Wu JR, Yeh JL. Liraglutide prevents and reverses monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways. Sci Rep. 2016 Sep 1;6:31788.
  7. Chang WT, Huang MC, Chung HF, Chiu YF, Chen PS, Chen FP, Lee CY, Shin SJ, Hwang SJ, Huang YF, Hsu CC. Interleukin-6 gene polymorphisms correlate with the progression of nephropathy in Chinese patients with type 2 diabetes: A prospective cohort study. Diabetes Res Clin Pract. 2016 Oct;120:15-23.
  8. Hsieh HM, Shin SJ, Tsai SL, Chiu HC. Effectiveness of Pay-for-Performance Incentive Designs on Diabetes Care. Med Care. 2016 Dec;54(12):1063-1069.
  9. Lin KD, Yang CY, Lee MY, Ho SC, Liu CK, Shin SJ*. Statin therapy prevents the onset of Parkinson disease in patients with diabetes. Ann Neurol. 2016 Oct;80(4):532-40.
  10. Liang CC, Lin PC, Lee MY, Chen SC, Shin SJ, Hsiao PJ, Lin KD, Hsu WH. Association of Serum Uric Acid Concentration with Diabetic Retinopathy and Albuminuria in Taiwanese Patients with Type 2 Diabetes Mellitus. Int J Mol Sci. 2016 Aug 2;17(8). pii: E1248.
  11. Chen CH, Ke LY, Chan HC, Lee AS, Lin KD, Chu CS, Lee MY, Hsiao PJ, Hsu C, Chen CH, Shin SJ*. Electronegative Low-Density Lipoprotein Induces Renal Apoptosis and Fibrosis: STRA6 Signaling Involved. J Lipid Res. 2016 Aug;57(8):1435-46.
  12. Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB; LEADER Steering Committee; LEADER Trial Investigators (Shin SJ). Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2016 Jul 28;375(4):311-22.
  13. Lee CW, Su H, Wu KD, Shiea J*, Wu DC, Chen BH*, Shin SJ. Rapid point-of-care identification of oral medications in gastric lavage content by ambient mass spectrometry in the emergency room. Rapid Commun Mass Spectrom. 2016 Jun 15;30(11):1295-303.
  14. Wang RH, Hsu HC, Lee YJ, Shin SJ, Lin KD, An LW. Patient empowerment interacts with health literacy to associate with subsequent self-management behaviors in patients with type 2 diabetes: A prospective study in Taiwan. Patient Educ Couns. 2016 Apr 4. pii: S0738-3991(16)30153-7.
  15. Hsieh HM, Lin TH, Lee IC, Huang CJ, Shin SJ, Chiu HC. The association between participation in a pay-for-performance program and macrovascular complications in patients with type 2 diabetes in Taiwan: A nationwide population-based cohort study. Prev Med. 2016 Apr;85:53-9.
  16. Lee CW, Su H, Chen PY, Lin SJ, Shiea J, Shin SJ, Chen BH*. Rapid identification of pesticides in human oral fluid for emergency management by thermal desorption electrospray ionization/mass spectrometry. J Mass Spectrom. 2016 Feb;51(2):97-104.
  17. Lee HC, Lin HT, Ke LY, Wei C, Hsiao YL, Chu CS, Lai WT, Shin SJ, Chen CH, Sheu SH, Wu BN. VLDL from Metabolic Syndrome Individuals Enhanced Lipid Accumulation in Atria with Association of Susceptibility to Atrial Fibrillation. Int J Mol Sci. 2016 Jan 20;17(1).
  18. Huang JF, Yeh ML, Yu ML, Huang CF, Dai CY, Hsieh MY, Hsieh MH, Huang CI, Lin ZY, Chen SC, Hsiao PJ, Shin SJ, Chuang WL* Hyperuricemia Inversely Correlates with Disease Severity in Taiwanese Nonalcoholic Steatohepatitis Patients. PLoS One. 2015 Oct 6;10(10):e0139796.
  19. Lee YJ, Shin SJ, Wang RH, Lin KD, Lee YL, Wang YH. Pathways of empowerment perceptions, health literacy, self-efficacy, and self-care behaviors to glycemic control in patients with type 2 diabetes mellitus. Patient Educ Couns. 2016 Feb;99(2):287-94. doi: 10.1016/j.pec.2015.08.021.
  20. Chen SC, Hsiao PJ, Huang JC, Lin KD, Hsu WH, Lee YL, Lee MY*, Chang JM, Shin SJ. Abnormally Low or High Ankle-Brachial Index Is Associated with Proliferative Diabetic Retinopathy in Type 2 Diabetic Mellitus Patients. PLoS One. 2015 Jul 31;10(7):e0134718. doi: 10.1371/journal.pone.0134718. eCollection 2015.
  21. Hsieh HM, Gu SM, Shin SJ, Kao HY, Lin YC, Chiu HC. Cost-Effectiveness of a Diabetes Pay-For-Performance Program in Diabetes Patients with Multiple Chronic Conditions. PLoS One. 2015 Jul 14;10(7):e0133163. doi: 10.1371/journal.pone.0133163. eCollection 2015.
  22. Lee MY, Lin KD, Hsu WH, Chang HL, Yang YH, Hsiao PJ, Shin SJ*. Statin, calcium channel blocker and Beta blocker therapy may decrease the incidence of tuberculosis infection in elderly taiwanese patients with type 2 diabetes. Int J Mol Sci. 2015 May 18;16(5):11369-84.
  23. Lee YL, Chen BK, Lin K, Su RW, Lee MY, Hsiao PJ, Shin SJ*. The impact of severe hypoglycemia on renal impairment in type 2 diabetes. Diabetes Res Clin Pract. 2015 Jun;108(3):448-55.
  24. Chung HF, Long KZ, Hsu CC, Al Mamun A, Jhang HR, Shin SJ, Hwang SJ, Huang MC. Association of n-3 polyunsaturated fatty acids and inflammatory indicators with renal function decline in type 2 diabetes. Clin Nutr. 2015 Apr;34(2):229-34.
  25. Hsieh HM, Tsai SL, Shin SJ, Mau LW, Chiu HC. Cost-Effectiveness of Diabetes Pay-for-Performance Incentive Designs. Med Care. 2015 Feb;53(2):106-15.
  26. Chen CY, Lee MY, Lin KD, Hsu WH, Lee YJ, Hsiao PJ*, Shin SJ*. Diabetes mellitus increases severity of thrombocytopenia in dengue-infected patients. Int J Mol Sci. 2015 Feb 10;16(2):3820-30.
  27. Cheng JS, Tsai WC, Lin CL, Chen L, Lang HC, Hsieh HM, Shin SJ, Chen T, Huang CT, Hsu CC. Trend and Factors Associated With Healthcare Use and Costs in Type 2 Diabetes Mellitus: A Decade Experience of a Universal Health Insurance Program. Med Care. 2015 Feb;53(2):116-24.
  28. Chang HY, Wahlqvist ML, Liu WL, Lee MS, Shin SJ, Li YS, Chang CJ, Chang CT, Fuh MT, Yang HJ, Tai TY, Hsu CC. Management trajectories in the type 2 diabetes Integrated Delivery System project in Taiwan: accounting for behavioral therapy, nutrition education and therapeutics. Asia Pac J Clin Nutr. 2014; 23(4):592-606. doi: 10.6133/apjcn. 2014.23.4.06.
  29. Chang YH, Lin KD, Shin SJ, Lee YJ. Changes in high-density-lipoprotein cholesterol upon statin treatment in type 2 diabetic patients: A meta-analysis. Nutr Metab Cardiovasc Dis. 2014 Oct;24(10):1067-73.
  30. Lin KD, Lee MY, Feng CC, Chen BK, Yu ML, Shin SJ*. Residual effect of reductions in red blood cell count and haematocrit and haemoglobin levels after 10-month withdrawal of pioglitazone in patients with Type 2 diabetes. Diabetic Med. 2014 Nov;31(11):1341-9. doi: 10.1111/dme.12481.
  31. Hsu PC, Wang CL, Su HM, Juo SH, Lin TH, Voon WC, Shin SJ, Lai WT, Sheu SH. The hOGG1 Ser326Cys gene polymorphism and the risk of coronary ectasia in the Chinese population. Int J Mol Sci. 2014 Jan 22;15(1):1671-82.
  32. Lee MY, Hsiao PJ, Yang YH, Lin KD, Shin SJ*. The Association of Pioglitazone and Urinary Tract Disease in Type 2 Diabetic Taiwanese: Bladder Cancer and Chronic Kidney Disease. PLoS One. 2014 Jan 10;9(1):e85479.
  33. Hsu CC, Jhang HR, Chang WT, Lin CH, Shin SJ, Hwang SJ, Huang MC. Associations between dietary patterns and kidney function indicators in type 2 diabetes. Clin Nutr. 2014 Feb;33(1):98-105.
  34. Hsu YH, Huang MC, Chang HY, Shin SJ, Wahlqvist ML, Chang YL, Hsu KC, Hsu CC. Association between serum ferritin and microalbuminuria in Type 2 diabetes in Taiwan. Diabetic Med. 2013 Nov;30(11):1367-73. doi: 10.1111/dme.12257.
  35. Hsu CC, Chang HY, Huang MC, Hwang SJ, Yang YC, Lee YS, Shin SJ*, Tai TY. HbA(1c) variability is associated with microalbuminuria development in type 2 diabetes: a 7-year prospective cohort study. Diabetologia. 2012 Dec;55(12):3163-72.
  36. Huang YY, Lin KD, Jiang YD, Chang CH, Chung CH, Chuang LM, Tai TY, Ho LT, Shin SJ*. Diabetes-related kidney, eye, and foot disease in Taiwan: An analysis of the nationwide data for 2000-2009. J Formos Med Assoc. 2012 Nov;111(11):637-44.
  37. Shin SJ*. Glucagon-like peptide-1 receptor agonists and their effects on weight reduction. (commtary) J Diabetes Invest. 2012 Dec;3(6):490-91.
  38. Hsu CC, Lee CH, Wahlqvist ML, Huang HL, Chang HY, Chen L, Shih SF, Shin SJ, Tsai WC, Chen T, Huang CT, Cheng JS. Poverty Increases Type 2 Diabetes Incidence and Inequality of Care Despite Universal Health Coverage. Diabetes Care. 2012 Nov;35(11):2286-92.
  39. Yu FJ, Huang MC, Chang WT, Chung HF, Wu CY, Shin SJ, Hsu CC. Increased ferritin concentrations correlate with insulin resistance in female type 2 diabetic patients. Ann Nutr Metab. 2012;61(1):32-40.
  40. Huang JF, Yu ML, Huang CF, Juo SH, Dai CY, Hsieh MY, Hou NJ, Yeh ML, Hsieh MH, Yang JF, Lin ZY, Chen SC, Shin SJ, Chuang WL. The outcomes of glucose abnormalities in pre-diabetic chronic hepatitis C patients receiving peginterferon plus ribavirin therapy. Liver Int. 2012 Jul;32(6):962-9.
  41. Chen CH, Hsieh TJ, Lin KD, Lin HY, Lee MY, Hung WW, Hsiao PJ, Shin SJ*. Increased unbound retinol binding protein 4 concentration induced apoptosis through its receptor-mediated signaling. J Biol Chem. 2012 Mar 23;287(13):9694-707.
  42. Lee MY, Lin KD, Hsiao PJ, Shin SJ*. The association of diabetes mellitus with liver, colon, lung, and prostate cancer is independent of hypertension, hyperlipidemia, and gout in Taiwanese patients. Metabolism. 2012 Feb;61(2):242-9.
  43. Hsieh TJ, Lin T, Hsieh PC, Liao MC, Shin SJ*. Suppression of Glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes. J Cell Physiol. 2012 Jan;227(1):108-15.
  44. Hsieh TJ, Hsieh PC, Wu MT, Chang WC, Hsiao PJ, Lin KD, Chou PC, Shin SJ*. Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes. Cell Biol Toxicol. 2011 Dec;27(6):397-411.
  45. Wang CW, Lin HY, Shin SJ, Yu ML, Lin ZY, Dai CY, Huang JF, Chen SC, Li SS, Chuang WL. The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population. Liver Int. 2011 Oct;31(9):1326-1331.
  46. Huang JF, Dai CY, Yu ML, Huang CF, Huang CI, Yeh ML, Yang JF, Hou NJ, Hsiao PJ, Lin ZY, Chen SC, Shin SJ, Chuang WL. Pegylated interferon plus ribavirin therapy improves pancreatic β-cell function in chronic hepatitis C patients. Liver Int. 2011 Sep;31(8):1155-62.
  47. Chang YH, Chang DM, Lin KC, Shin SJ, Lee YJ. Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome, and cardiovascular diseases: A meta-analysis and systemic review. Diabetes-Metab Res. 2011 Sep;27(6):515-27.
  48. Chang YH, Lin KD, He SR, Hsieh MC, Hsiao JY, Shin SJ*. Serum osteoprotegerin and tumor necrosis factor related apoptosis inducing-ligand (TRAIL) are elevated in type 2 diabetic patients with albuminuria and serum osteoprotegerin is independently associated with the severity of diabetic nephropathy. Metabolism. 2011 Aug;60(8):1064-9.
  49. Hsu CC, Chang HY, Huang MC, Hwang SJ, Yang YC, Tai, TY, Yang HJ, Chang CZ, Chang CJ, Li, YS, Shin SJ*, Kuo KN. Association between Insulin Resistance and Development of Microalbuminuria in Type 2 Diabetes: A Prospective Cohort Study. Diabetes Care. 2011 Apr;34(4):982-7.
  50. Tien KJ, Tu ST, Chou CW, Yang CY, Hsiao JY, Shin SJ, Chen HC, Hsieh MC. Apolipoprotein E Polymorphism and the Progression of Diabetic Nephropathy in Type 2 Diabetes. Am J Nephrol. 2011;33(3):231-8.
  51. Hung WW, Hsieh TJ, Lin T, Chou PC, Hsiao PJ, Lin KD, Shin SJ*. Blockade of the Renin-Angiotensin System Ameliorates Apelin Production in 3T3-L1 Adipocytes. Cardiovasc Drug Ther. 2011 Feb;25(1):3-12.
  52. Lin TH, Wang CL, Su HM, Hsu PC, Juo SH, Voon WC, Shin SJ, Lai WT, Sheu SH. Functional vascular endothelial growth factor gene polymorphisms and diabetes: effect on coronary collaterals in patients with significant coronary artery disease. Clin Chim Acta. 2010 Nov 11;411(21-22):1688-93.
  53. Wang CL, Lin TH, Lin HY, Sheu SH, Yu ML, Hsiao PJ, Lin KD, Hsu C, Yang YH, Shin SJ*. The 8-oxoguanine glycosylase I (hOGG1) Ser(326)Cys variant affects the susceptibility to multi-vessel disease in Taiwan coronary artery disease patients. Thromb Res. 2010 Oct;126(4):319-23.
  54. Lin TH, Su HM, Wang CL, Voon WC, Shin SJ, Lai WT, Sheu SH. Vascular endothelial growth factor polymorphisms and extent of coronary atherosclerosis in Chinese population with advanced coronary artery disease. Am J Hypertens. 2010 Sep;23(9):960-6.
  55. Lee MY, Lin KD, Chang YH, Hsiao PJ, Shin SJ*. Albuminuria Is the Stronger Risk Factor for Peripheral Arterial Disease than eGFR Decline in a Type 2 Diabetic Taiwanese Population. Kidney Blood Press R. 2010 Aug 12;33(5):352-59.
  56. Hung WC, Wang CP, Lu LF, Yu TH, Chiu CA, Chung FM, Chen HJ, Houng JY, Shin SJ, Lee YJ. Circulating adiponectin level is associated with major adverse cardiovascular events in type 2 diabetic patients with coronary artery disease. Endocr J. 2010 Sep 29;57(9):793-802.
  57. Hsieh MC, Lin KD, Tien KJ, Tu ST, Hsiao JY, Chang SJ, Lin SR, Shing SJ, Chen HC.  Common polymorphisms of the peroxisome proliferator-activated receptor-gamma (Pro12Ala) and peroxisome proliferator-activated receptor-gamma coactivator-1 (Gly482Ser) and the response to pioglitazone in Chinese patients with type 2 diabetes mellitus. Metabolism. 2010 Aug;59(8):1139-44.
  58. Lee MY, Lin KD*, Chang YH, Hsieh MC, Hsiao PJ, Shin SJ. 2010. Fulminant type 1 diabetes mellitus leading to fetal loss in a pregnant Chinese woman. Kaohsiung J Med Sci Jun;26(6):316-20.
  59. Wang CP, Hung WC, Yu TH, Chiu CA, Lu LF, Chung FM, Hung CH, Shin SJ, Chen HJ, Lee YJ. Genetic Variation in the G-50T Polymorphism of the Cytochrome P450 Epoxygenase CYP2J2 Gene and the Risk of Younger Onset Type 2 Diabetes among Chinese Population: Potential Interaction with Body Mass Index and Family History. Exp Clin Endocr Diab. 2010 Jun;118(6):346-52.
  60. Lin HY, Li SS, Yu ML, Hsiao PJ, Hsieh MC, Lin KD, Wang CL, Wang TN, Shin SJ*. Small ubiquitin-like modifier-4 Met55Val polymorphism is associated with glycemic control of type 2 diabetes mellitus in Taiwan. J Endocrinol Invest. 2010 Jun;33(6):401-5.
  61. Hsu CC, Hwang SJ, Tai TY, Chen T, Huang MC, Shin SJ, Wen CP, Shih YT, Yang HJ, Chang CT, Chang CJ, Loh CH, Fuh MT, Li YS, Chang HY. Cigarette smoking and proteinuria in Taiwanese men with Type 2 diabetes mellitus. Diabetic Med. 2010 Mar;27(3):295-302.
  62. Huang MC, Hsu CC, Wang HS, Shin SJ*. Prospective randomized controlled trial to evaluate effectiveness of registered dietitian led diabetes management on glycemic and diet control in a primary care setting in Taiwan. Diabetes Care. 2010 Feb;33(2):233-9.
  • (B) 研究計畫

    1. OGG1酵素在脂肪細胞胰島素抗阻性分子機轉的調控(QM094009-MR-0010)(1/2)-高雄醫學大學
    2. Adipokine對細胞傷害和保護的訊息傳遞(1/3) (NSC95-2314-B-037-040-MY3)-國科會
    3. SUMO4基因在糖尿病腎病變之探討(1/3) (NSC96-2314-B-037-023-MY3)-國科會
    4. 生活行為改變對潛伏性糖尿病之糖尿病防治-衛生署
    5. 腎小管細胞在高葡萄糖下心房利鈉胜(月太)對粒線體功能的調控-高醫附院獎勵計畫
    6. 脂肪代謝基因、發炎基因與n-3多元不飽和脂肪酸對糖尿病以及糖尿病腎病變之影響(97-2320-B-037-021-)-國科會(共同主持人)
    7. Adiponectin/adiponectin 接受體基因多型性/基因表現與飲食脂肪酸組成對糖尿病以及糖尿病腎病變之影響(98-2314-B-037-044-MY3)-國科會(共同主持人)
    8. PCTA調控蛋白在高糖環境刺激下對腎臟間質細胞TGF-β代謝路徑的影響(98-2314-B-037-012-)-國科會(共同主持人)
    9. PEPCK 基因在非酒精性脂肪肝之探討(98-2314-B-037-013-MY2)-國科會(共同主持人)
    10. 血清脂肪細胞激素/細胞激素值動態變化與非酒精性脂肪性肝炎病患以Peroxisome proliferator–activated receptor-gamma 觸效劑治療與否之研究(98-2314-B-037-043-MY3)-國科會(共同主持人)
    11. O-GlcNAc修飾蛋白質在人類脂肪細胞分化及脂質新生過程中之作用(98-2314-B-037-011-MY3)-國科會(共同主持人)
    12. 慢性C型肝炎病患血糖異常之功能基因體學研究(98-2314-B-037-059-MY3) -國科會(共同主持人)
    13. 人類腎小管細胞Endogenous Cellular Retinol Binding Protein對高葡萄糖刺激TGF-β, Smad生成和細胞凋亡之訊息傳遞 -高醫附院獎勵計畫
    14. 一個雙盲、隨機、以安慰劑為對照組之第二期臨床試驗,評估Pioglitazone對於非酒精性脂肪性肝炎之療效及安全性-國科會(共同主持人)
    15. 在無高血壓家族史的年輕型高血壓患者身上氧化壓力及其相關基因多型性對年輕型高血壓的臨床表現與治療的影響-國科會(共同主持人)
    16. 腎臟合成angiotensinogen 和 atrial natriuretic peptide 的 交互作用(100-2314-B-037-013-)-國科會
    17. Retinol-Binding Protein對高葡萄糖誘發內皮細胞自然凋亡之影響-國科會
    18. VLDL5在脂肪細胞和橫紋肌細胞經Retinol binding prtoein receptor 4接受器訊息路徑誘發胰島素阻抗性-科技部
    19. 慢性C型肝炎病患血糖異常的致病機轉研究-科技部(共同主持人)
    20. 控制血壓以降低第2型糖尿病腎臟病變風險之研究-國衛院
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