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論文發表

  1. Du JS, Hsu SH, Shen-Nien Wang*. The Current and Prospective Adjuvant Therapies for Hepatocellular Carcinoma. Cancers (Basel). 2024 Apr 6;16(7):1422.
  2. Wu PH, Yu MW, Chuang SC, Shen-Nien Wang, Kuo KK, Chang WT, Chuang SH, Su WL, Huang JW, Chen LA.Comparison of laparoscopic common bile duct exploration plus cholecystectomy and endoscopic retrograde cholangiopancreatography followed by laparoscopic cholecystectomy for elderly patients with common bile duct stones and gallbladder stones. J Gastrointest Surg. 2024 Mar 1:S1091-255X(24)00332-9.
  3. Chen GY, Kuo KK, Chuang SC, Tseng KY, Shen-Nien Wang, Chang WT, Cheng KI. Optimal Post-Operative Nalbuphine Dose Regimen: A Randomized Controlled Trial in Patients with Laparoscopic Cholecystectomy.Medicina (Kaunas). 2024 Jan 23;60(2):195.
  4. Wang LT, Shen-Nien Wang, Chiou SS, Tsai JP, Chai CY, Tseng LW, Lee JC, Lin MH, Huang SK, Hsu SH. HCV Core Protein-ISX Axis Promotes Chronic Liver Disease Progression via Metabolic Remodeling and Immune Suppression.Adv Sci (Weinh). 2023 Aug;10(23):e2300644.
  5.  Wang LT, Liu KY, Shen-Nien Wang, Lin MH, Liao YM, Lin PC, Huang SK, Hsu SH, Chiou SS.Cell Biol Toxicol. Aryl hydrocarbon receptor-kynurenine axis promotes oncogenic activity in BCP-ALL.2023 Aug;39(4):1471-1487.
  6. Yu GK, Shen-Nien Wang*. Obstructive jaundice caused by IgG4-related disease with multiorgan involvement. Kaohsiung J Med Sci. 2023 May;39(5):546-547.
  7. Dai HY, Chang LS, Yang SF, Shen-Nien Wang,Su SJ, Yeh YT. HDAC6 promotes aggressive development of liver cancer by improving egfr mRNA stability. Neoplasia. 2023 Jan;35:100845.
  8.  Chuang SH, Kuo KK, Chuang SC, Shen-Nien Wang, Chang WT, Su WL, Huang JW, Wu PH, Chan HM, Kuok CH. Single-incision versus four-incision laparoscopic transfistulous bile duct exploration for Mirizzi syndrome type II Surg Endosc.  2022 Nov;36(11):8672-8683.
  9. Wang LT, Liu KY, Chiou SS, Huang SK, Hsu SH, Shen-Nien Wang*. Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. Cancer Lett. 2021(1);520:160-171.
  10.  Wang LT, Lin MH, Liu KY, Chiou SS, Shen-Nien Wang, Chai CY, Tseng LW, Chiou HC, Wang HC, Yokoyama KK, Hsu SH, Huang SK*. WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism. Autophagy. 2021;14:1-16.
  11. Liu KY, Wang LT, Wang HC, Shen-Nien Wang, Tseng LW, Chai CY, Chiou SS, Huang SK, Hsu SH*. Aryl Hydrocarbon Receptor is Essential in the Control of Lung Club Cell Homeostasis. J Inflamm Res. 2021;14:299-311. 
  12. Chuang KT, Shen-Nien Wang, Hsu SH, Wang LT*. Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma for better clarity. Cancer Med. 2021;10(16):5545-5556.
  13.  Wang LT, Liu KY, Jeng WY, Chiang CM, Chai CY, Chiou SS, Huang MS, Yokoyama KK, Shen-Nien Wang, Huang SK, Hsu SH*. PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition. EMBO Rep. 2020;21(2):e48795.
  14. Su WL, Chuang SC, Wang YC, Chen LA, Huang JW, Chang WT, Shen-Nien Wang, Lee KT, Lin CS, Kuo KK*. Expression of FOXM1 and Aurora-A predicts prognosis and sorafenib efficacy in patients with hepatocellular carcinoma. Cancer Biomark. 2020;28(3):341-350. 
  15. Han HS, Kim HJ, He J, Lee JH, Takaori K, Marino MV, Shen-Nien Wang, Guo T, Hackert T, Huang TS, Anusak Y, Fong Y, Nagakawa Y, Shyr YM, Wu YM, Zhao Y. International consensus statement on robotic pancreatic surgery. Hepatobiliary Surg Nutr. 2019;8(4):345-360.
  16. Liu KY, Wang LT, Hsu SH, Shen-Nien Wang*. Homeobox Genes and Hepatocellular Carcinoma. Cancers (Basel). 2019 May 3;11(5).
  17. Wang LT, Shen-Nien Wang, Chiou SS, Liu KY, Chai CY, Chiang CM, Huang SK, Yokoyama KK, Hsu SH. TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial-mesenchymal transition and metastasis in liver cancer. Oncogene. 2019;38:518-532.
  18. Huang JW, Su WL, Shen-Nien Wang*. Alternative Laparoscopic Intracorporeal Pringle Maneuver by Huang's Loop. World J Surg. 2018;42:3312-3315.
  19. Wang WH, Kuo KK, Shen-Nien Wang, Lee KT. Oncological and surgical result of hepatoma after robot surgery. Surg Endosc. 2018;32:3918-3924. 
  20. Chen WC, Tseng CK, Lin CK, Shen-Nien Wang, Wang WH, Hsu SH, Wu YH, Hung LC, Chen YH, Lee JC. Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1. Virulence. 2018;9:588-603.
  21. Wang LT, Chiou SS, Chai CY, Hsi E, Yokoyama KK, Shen-Nien Wang*, Huang SK*, Hsu SH*. Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. Cancer Res. 2017;77:4065-4077.
  22. Hsu SH, Wang LT, Chai CY, Wu CC, Hsi E, Chiou SS, Shen-Nien Wang*. Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine-specific homeobox expression. Mol Carcinog. 2017;56:2167-2177.
  23. Wang LT, Chiou SS, Chai CY, Hsi E, Chiang CM, Huang SK, Shen-Nien Wang*, Yokoyama KK*, Hsu SH*. Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer. Oncogene. 2017;36:4405-4414.
  24. Li YP, Shen-Nien Wang, Lee KT. Robotic versus conventional laparoscopic cholecystectomy: A comparative study of medical resource utilization and clinical outcomes. Kaohsiung J Med Sci. 2017;33:201-206.
  25. Wang LT, Chiou SS, Chai CY, Hsi E, Shen-Nien Wang*, Huang SK*, Hsu SH*. Aryl hydrocarbon receptor regulates histone deacetylase 8 expression to repress tumor suppressive activity in hepatocellular carcinoma. Oncotarget. 2017;8:7489-7501.
  26. Chen YC, Chen LA, Lin CH, Shen-Nien Wang*. Undifferentiated pancreatic carcinoma with osteoclast-like giant cells: A rare entity with potential misdiagnosis of a gastrointestinal stromal tumor on preoperative evaluation. Kaohsiung J Med Sci. 2016;32:593-594.
  27. Su WL, Huang JW, Shen-Nien Wang, Lee KT. Comparison study of clinical outcomes between single-site robotic cholecystectomy and single incision laparoscopic cholecystectomy. Asian J Surg. 2016 May 14. [Epub ahead of print]
  28. Shen-Nien Wang, Wang LT, Sun DP, Chai CY, Hsi E, Kuo HT, Yokoyama KK, Hsu SH. Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC. Oncotarget. 2016;7:36924-36939.
  29. Chang WT, Kuo YT, Lee KT, Shih MC, Huang JW, Su WL, Chen CY, Huang YL, Shen-Nien Wang, Chuang SC, Kuo KK, Chen JS. The value of primary vascular stents in management of early portal vein stenosis after liver transplantation. Kaohsiung J Med Sci. 2016;32:128-34.
  30. Chen WC, Tseng CK, Chen YH, Lin CK, Hsu SH, Shen-Nien Wang, Lee JC.  HCV NS5A Up-Regulates COX-2 Expression via IL-8-Mediated Activation of the ERK/JNK MAPK Pathway. PLoS One. 2015 Jul 31;10(7):e0133264.
  31. Chiou SS, Wang LT, Huang SB, Chai CY, Shen-Nien Wang, Liao YM, Lin PC, Liu KY, Hsu SH*. Wntless (GPR177) expression correlates with poor prognosis in B-cell precursor acute lymphoblastic leukemia via Wnt signaling. Carcinogenesis. 2014;35:2357-64.
  32. Yang SF, Chang CW, Wei RJ, Shiue YL, Shen-Nien Wang*, Yeh YT*. Involvement of DNA damage response pathways in hepatocellular carcinoma. Biomed Res Int. 2014;2014:153867. 
  33. Shi HY, Shen-Nien Wang, Wang SC, Chuang SC, Chen CM, Lee KT. Preoperative transarterial chemoembolization and resection for hepatocellular carcinoma: a nationwide Taiwan database analysis of long-term outcome predictors. J Surg Oncol. 2014;109:487-93. 
  34. Shi HY, Shen-Nien Wang, Lee KT. Temporal trends and volume-outcome associations in periampullary cancer patients: a propensity score-adjusted nationwide population-based study. Am J Surg. 2014;207:512-9. 
  35. Shen-Nien Wang, Yang SF, Tsai HH, Lee KT, Yeh YT. Increased adiponectin associated with poor survival in hepatocellular carcinoma. J Gastroenterol. 2014;49:1342-51.
  36. Wen-Wen Chou, Yu-Ting Wang, Yi-Chu Liao, Shih-Chang Chuang, Shen-Nien Wang, Suh-Hang Hank Juo*. Decreased microRNA-221 is associated with high levels of TNF-α in human adipose tissue-derived mesenchymal stem cells from obese woman. Cell Physiol Biochem. 2013;32:127-37.
  37. Hsu SH, Yeh ML, Shen-Nien Wang*. New insights in recurrent HCV infection after liver transplantation. Clin Dev Immunol. 2013:890517.
  38. Yeh YT, Chang CW, Wei RJ, Shen-Nien Wang*. Progesterone and related compounds in hepatocellular carcinoma: basic and clinical aspects. Clin Dev Immunol 2013:890517.  
  39. Chen JS, Chuang SC, Shen-Nien Wang, Chang WT, Kuo KK, Lee KT, Ker CG. Natural course of splenic artery aneurysm with associated spontaneous splenorenal shunt in non-cirrhotic liver: An 18-year observational follow-up and review of literature. Kaohsiung J Med Sci. 2013;29:55-8.
  40. Hsu SH, Wang LT, Lee KT, Chen YL, Liu KY, Suen JL, Chai CY, Shen-Nien Wang*. Pro-Inflammatory Homeobox Gene, ISX, Regulates Tumor growth and Survival in Hepatocellular Carcinoma. Cancer Res. 2013;73: 508-518. 
  41. Shen-Nien Wang, Lee KT, Tsai CJ, Chen YJ, Yeh YT. Phosphorylated p38 and JNK MAPK proteins in hepatocellular carcinoma. Eur J Clin Invest. 2012;42:1295-1301.
  42. Wong KM, Yeh ML, Chuang SC, Wang LY, Lin ZY, Chen SC, Tsai JF, Shen-Nien Wang, Kuo KK, Dai CY, Yu ML, Lee KT, Chuang WL. Survival comparison between surgical resection and percutaneous radiofrequency ablation for patients in Barcelona Clinic Liver Cancer early stage hepatocellular carcinoma. Indian J Gastroenterol. 2012 Aug 30. [Epub ahead of print]
  43. Hou MF, Chang CW, Chen FM, Shen-Nien Wang, Yang SF, Chen PH, Su JH, Yeh YT. Decreased total MKP-1 protein levels predict poor prognosis in breast cancer. World J Surg. 2012;36(8):1922-32.
  44. Lee KT, Shen-Nien Wang, Su RW, Chen HY, Shi HY, Ker CG, Chiu HC. Is wider surgical margin justified for better clinical outcomes in patients with resectable hepatocellular carcinoma? J Formos Med Assoc. 2012;111(3):160-70. 
  45. Yeh YT, Lee KT, Tsai CJ, Chen YJ, Shen-Nien Wang*. Prolactin promotes hepatocellular carcinoma through Janus kinase 2. World J Surg. 2012;36(5):1128-35.
  46. Chen MJ, Yeh YT, Lee KT, Tsai CJ, Lee HH, Shen-Nien Wang*. The promoting effect of adiponectin in hepatocellular carcinoma. Surg Oncol. 2012;106(2):181-7.
  47. Shen-Nien Wang, Wang ST, Lee KT. The potential interplay of adipokines with toll-like receptors in the development of hepatocellular carcinoma. Gastroenterol Res Pract. 2011;2011:215986. 
  48. Chuang SC, Hsi E, Shen-Nien Wang, Yu ML, Lee KT, Juo SH. Polymorphism at the mucin-like protocadherin gene influences susceptibility to gallstone disease. Clin Chim Acta. 2011;412(23-24):2089-93. 
  49. Chen ML, Chai CY, Yeh KT, Shen-Nien Wang, Tsai CJ, Yeh YT, Yang SF. Crosstalk between activated and inactivated c-Src in hepatocellular carcinoma. Dis Markers. 2011;30(6):325-33. 
  50. Shen-Nien Wang, Lee KT, Ker CG. Leptin in hepatocellular carcinoma. World J Gastroenterol. 2010;16(46):5801-9.
  51. Chuang SC, Juo SH, Hsi E, Shen-Nien Wang, Tsai PC, Yu ML, Lee KT. Multiple mucin genes polymorphisms are associated with gallstone disease in Chinese men. Clin Chim Acta 2011;412:599-603.
  52. Yang SF, Yang JY, Huang CH, Shen-Nien Wang, Lu CP, Tsai CJ, Chai CY, Yeh YT. Increased caveolin-1 expression associated with prolonged overall survival rate in hepatocellular carcinoma. Pathology 2010;42:438-45
  53. Shen-Nien Wang, Yeh YT, Wang ST, Chen YL, Chuang SC, Ker CG, Lee KT. Decreased retinol binding protein 4 concentrations are associated with cholesterol gallstone disease. J Formos Med Assoc 2010;109:422-9.
  54. Shen-Nien Wang, Yeh YT, Wang ST, Chuang SC, Wang CL, Yu ML, Lee KT. Visfatin--a proinflammatory adipokine-in gallstone disease. Am J Surg 2010;199:459-65. 
  55. Chang WT, Yu FJ, Hsieh MY, Huang MC, Lee KT, Chen JS, Kuo KK, Chuang SC, Shen-Nien Wang, Ker CG. Laparoscopic cholecystectomy in aged patients. Hepatogastroenterology 2009;56:950-5.
  56. Chang WT, Lee KT, Huang MC, Chen JS, Chiang HC, Kuo KK, Chuang SC, Shen-Nien Wang, Ker CG. The impact of body mass index on laparoscopic cholecystectomy in Taiwan: an oriental experience. J Hepatobiliary Pancreat Surg 2009;16:648-54.
  57. Lee KT, Lu YW, Shen-Nien Wang, Chen HY, Chuang SC, Chang WT, Shi HY, Ker CG, Chiu HC. The effect of preoperative transarterial chemoembolization of resectable hepatocellular carcinoma on clinical and economic outcomes. J Surg Oncol 2009;99:343-50.
  58. Sheau-Fang Yang, Yao-Tsung Yeh, Shen-Nien Wang, Sz-Chi Hung, Wan-Tzu Chen, Chu-Ho Huang, Chee-Yin Chai. SOCS-3 is associated with vascular invasion and overall survival in hepatocellular carcinoma. Pathology 2008;40:558-63.
  59. Shen-Nien Wang, Mark Sturdevant, Raja Kandaswamy, Rainer G.W. Gruessner, David E.R. Sutherland and Abhinav Humar. Technical failure of the pancreas after SPK transplant: are these patients good candidates for later pancreas retransplant? Clin Transplant 2008;22:50-4.
  60. Chang HW, Tsui KH, Shen LC, Huang HW, Shen-Nien Wang, Chang PL. Urinary cell-free DNA as a potential tumor marker for bladder cancer. Int J Biol Markers 2007;22:287-94.
  61. King-Teh Lee, Shih-Meng Tsai, Shen-Nien Wang, Shu-Kai Lin, Szu-Hwa Wu, Shih-Chung Chuang, Szu-Hsien Wu, Hsu Ma and Li-Yu Tsai. Glutathione status in the blood and tissues of patients with virus-originated hepatocellular carcinoma. Clin Biochem 2007;40:1157-62. 
  62. Sheau-Fang Yang, Shen-Nien Wang, Chih-Fung Wu, Yao-Tsung Yeh, Chee-Yin Chai, Shih-Chang Chunag, Maw-Chang Sheen, King-Teh Lee. Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma. J Clin Pathol 2007;60:642-8.
  63. Shen-Nien Wang, K-B Tsai, K-T Lee. Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review. J Clin Pathol 2006;59:1196-9.
  64. King-Teh Lee, Wen-Tsan Chang, Shen-Nien Wang, Shih-Chang Chuang, Chee-Yin Chai, Shih-Wen Hu. Expression of DPC4/Smad4 gene in stone-containing intrahepatic bile duct. J Surg Oncol 2006;94:338-43. 
  65. Chuang SC, Lee KT, Shen-Nien Wang, Kuo KK, Chen JS. Hypertriglyceridemia-associated acute pancreatitis with chylous ascites in pregnancy. J Formos Med Assoc 2006;105:583-7.
  66. Shen-Nien Wang, Y.-T. Yeh, M.-L. Yu, C.-L. Wang, K.-T. Lee. Serum adiponectin levels in cholesterol and pigment cholelithiasis. Br J Surg 2006;93:981-6.
  67. Wen-Tsan Chang, King-Teh Lee M.D, Shih-Chang Chuang, Shen-Nien Wang, Kung-Kai Kuo, Jong-Shyone Chen and Pai-Ching Sheen. The impact of prophylactic antibiotics on postoperative infection complication in elective laparoscopic cholecystectomy: a prospective randomized study. Am J Surg 2006;191:721-5.
  68. Shen-Nien Wang, Chuang SC, Tsai KB, Chai CY, Chang WT, Kuo KK, Chen JS, Lee KT. Aberrant p53 expression and the development of gallbladder carcinoma and adenoma. Kaohsiung J Med Sci 2006;22:53-9. 
  69. Shen-Nien Wang, S-C Chuang, Y-T Yeh, S-F Yang, C-Y Chai, W-T Chen, K-K Kuo, J-S Chen, K-T Lee. Potential prognostic value of leptin receptor in hepatocellular carcinoma. J Clin Pathol 2006;59:1267-71.
  70. Shen-Nien Wang, Y-T Yeh, S-F Yang, C-Y Chai, K-T Lee. Potential role of leptin expression in hepatocellular carcinoma. J Clin Pathol 2006;59:930-4.
  71. Shen-Nien Wang, YT Yeh, ML Yu, CY Dai, WC Chi, WL Chung and KT Lee. Hyperleptinaemia and hypoadiponectinaemia are associated with gallstone disease. Eur J Clin Invest 2006;36:176-80.
  72. Mei-Chin Lu, Sheng-Huei Yang, Shiuh-Lin Hwang, Yu-Jhang Lu, Yi-Hsiung Lin, Shen-Nien Wang, Yang-Chang Wu and Shinne-Ren Lin. Induction of G2/M phase arrest by squamocin in chronic myeloid leukemia (K562) cells. Life Sci. 2006;78:2378-83.
  73. Chuang SC, Lee KT, Chang WT, Shen-Nien Wang, Kuo KK, Chen JS, Sheen PC. Risk factors for wound infection after cholecystectomy. J Formos Med Assoc 2004;103:607-12.
  74. Shiuh-Lin Hwang, Chih-Lung Lin, Ann-Shung Lieu, Tai-Hung Kuo, Kwong-Leung Yu, Fu Ou-Yang, Shen-Nien Wang, King-Teh Lee and Shen-Long Howng. Punctate midline myelotomy for intractable visceral pain caused by hepatobiliary or pancreatic cancer. J Pain Symptom Manage 2004;27:79-84.
  75. Kuo KK, Sheen PC, Lee KT, Sheen MC, Chuang SC, Shen-Nien Wang, Wang WM. Bile duct cancer 25 years after choledochoduodenostomy: a case report. Kaohsiung J Med Sci 2002;18:466-70.
  76. Chuang SC, Sheen PC, Chang WT, Shen-Nien Wang, Kuo KK, Chen JS, Lee KT. Solid and cystic tumor of the pancreas--three cases report. Kaohsiung J Med Sci 2002;18:314-8.
  77. Chang WT, Lee KT, Shen-Nien Wang, Chuang SC, Kuo KK, Chen JS, Sheen PC. Bacteriology and antimicrobial susceptibility in biliary tract disease: an audit of 10-year's experience. Kaohsiung J Med Sci 2002;18:221-8.
  78. Lee KT, Shen-Nien Wang, Sheen PC. Pyogenic liver abscess: an audit of 10 years' experience and analysis of risk factors. Dig Surg 2001;18:459-65.
  79. Lee KT, Shen-Nien Wang, Chen JS, Ker CG, Sheen PC, Liu YE. Ultrasound-guided percutaneous cholecystostomy as an initial treatment for acute cholecystitis in elderly patients. Dig Surg. 1998;15:328-32.
  80. Shen-Nien Wang, Lee KT, Kuo KK, Chen JS, Ker CG, Sheen PC. Pancreatic pseudocyst involving the spleen. Kaohsiung J Med Sci 1998;14:524-7.
  81. Shen-Nien Wang, Lee KT, Kuo KK, Chen JS, Ker CG, Sheen PC. Ultrasound-guided percutaneous transhepatic drainage of gallbladder followed by cholecystectomy for acute cholecystitis--10 years' experience. Kaohsiung J Med Sci 1998;14:19-24. 
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