醫│師│簡│介
李香君 醫師
專長臨床服務: 高血壓、心衰竭、心肌梗塞、冠狀動脈疾病、瓣膜性心臟病、心臟超音波檢查、心導管及介入性治療、心臟科急重症醫療、各種結構性心臟病介入治療之(食道)心臟超音波評估
醫學研究: 心律不整相關基因致病機轉之研究、基礎電生理研究、離子通道研究、脂質異常導致心肌病變與心律不整研究
現任職稱
高雄醫學大學附設中和紀念醫院心臟血管內科主治醫師 (2004/8~)
高雄醫學大學醫學院醫學系內科學教授 (2023/2~)
高雄醫學大學醫學院脂質科學暨老化研究中心主任(2019/1~)
中山大學醫學科技研究所合聘教授 (2014/8~)
中央健康保險署審查醫藥專家 (2016/4~)
中華民國心臟學會雜誌 Acta Cardiologica Sinica 執行編輯 (2017~)
高雄醫學大學附設中和紀念醫院心臟血管檢查室主任 (2020/8~)
國立屏東科技大學動物疫苗科技研究所合聘副教授（2020/8~）
中華民國心臟學會副秘書長 (2022/9~)
中華民國心臟學會專科指導醫師 (2022/12~)
高雄醫學大學醫學院醫學系內科學教授 (2023/2~)
高雄醫學大學醫學院脂質科學暨老化研究中心主任(2019/1~)
中山大學醫學科技研究所合聘教授 (2014/8~)
中央健康保險署審查醫藥專家 (2016/4~)
中華民國心臟學會雜誌 Acta Cardiologica Sinica 執行編輯 (2017~)
高雄醫學大學附設中和紀念醫院心臟血管檢查室主任 (2020/8~)
國立屏東科技大學動物疫苗科技研究所合聘副教授（2020/8~）
中華民國心臟學會副秘書長 (2022/9~)
中華民國心臟學會專科指導醫師 (2022/12~)
學歷
高雄醫學院醫學系學士 (1992- 1999)
高雄醫學大學醫學研究所臨床醫學組碩士 (2003- 2004)
美國聖路易斯華盛頓大學生物電機研究所訪問學者 (2010- 2012)
高雄醫學大學醫學研究所博士 (2008- 2016）
高雄醫學大學醫學研究所臨床醫學組碩士 (2003- 2004)
美國聖路易斯華盛頓大學生物電機研究所訪問學者 (2010- 2012)
高雄醫學大學醫學研究所博士 (2008- 2016）
經歷
高雄醫學大學附設中和紀念醫院內科住院醫師 (1999- 2002)
高雄醫學大學附設中和紀念醫院心臟內科總住院醫師 (2002- 2004)
中華民國心臟學會研究委員會委員 (2016- 2018)
高雄醫學大學醫學院國際組組長 (2018/12~ 2021/8)
高雄醫學大學附設中和紀念醫院心臟內科總住院醫師 (2002- 2004)
中華民國心臟學會研究委員會委員 (2016- 2018)
高雄醫學大學醫學院國際組組長 (2018/12~ 2021/8)
專科執照與學會
<執照>
醫師證書: 醫字第030991號 (1999)
內科專科醫師證書: 內專醫字第006324號 (2002)
心臟內科專科證書: (93)中心專醫字001號 (2004)
中華民國心臟學會心臟血管介入專科醫師: 0324 (2007)
中華民國重症醫學專科醫師: 00964 (2009)
<學會>
台灣內科醫學會會員 會員編號 6459
中華民國心臟學會會員 會員編號 S1043
中華民國醫用超音波學會 會員編號 H0587
中華民國高血壓學會會員
中華民國重症醫學會會員 會員編號 3258
美國心臟協會國際學術會員 (2011~)
中華民國血脂及動脈硬化學會會員（2018/6~）
醫師證書: 醫字第030991號 (1999)
內科專科醫師證書: 內專醫字第006324號 (2002)
心臟內科專科證書: (93)中心專醫字001號 (2004)
中華民國心臟學會心臟血管介入專科醫師: 0324 (2007)
中華民國重症醫學專科醫師: 00964 (2009)
<學會>
台灣內科醫學會會員 會員編號 6459
中華民國心臟學會會員 會員編號 S1043
中華民國醫用超音波學會 會員編號 H0587
中華民國高血壓學會會員
中華民國重症醫學會會員 會員編號 3258
美國心臟協會國際學術會員 (2011~)
中華民國血脂及動脈硬化學會會員（2018/6~）
備註說明
Publications (Selected)
1. Lee HC, Lin HT, Ke LY, Wei C, Hsiao YL, Chu CS, Lai WT, Shin SJ, Chen CH, Sheu SH, Wu BN. VLDL from metabolic syndrome individuals enhanced lipid accumulation in atria with association of susceptibility to atrial fibrillation. Int J Mol Sci. 2016;17:134.
2. Lee HC, Chiu CC, Chen CC, Huang JW, Lin HT, Hsiao YL, Sheu SH, Hsieh CC. Modulation of potassium channel KCNQ1 transcript in right atrial appendage of patients with postoperative atrial fibrillation. Int J Cardiol. 2016;222, p696-698 (published online: August 4, 2016)
3. Lee HC, Rudy Y, Liang H, Chen CC, Luo CH, Sheu SH, Cui J. Pro-arrhythmogenic effects of the V141M KCNQ1 mutation in short QT syndrome and its potential therapeutic targets - insights from modeling. J Med Biol Eng. 2017 Oct;37(5):780-789. 2017 Jul (Epub)
4. YL Shiou, IC Huang, HT Lin, Lee HC *. High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats. JFMA. 2017 Sep
5. Lee HC, CC Chen, WC Tsai, HT Lin, YL Shiao, SH Sheu, BN Wu, CH Chen, WT Lai. Very-low-density lipoprotein of metabolic syndrome modulates gap junctions and slows cardiac conduction. Sci Rep. 2017 Sep 21;7(1):12050.
6. Lee HC, Lin TH. Air pollution particular matter and atherosclerosis. Acta Cardiol Sin. 2017 Nov; 33(6): 646-647.
7. Lin HT, Shiou YL, Jhuang WJ, Lee HC*. Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats. J. Vis. Exp (JoVE) 2019. (143), e59115, doi:10.3791/59115.
8. Lee HC, Shiou YL, Jhuo SJ, Chang CY, Liu PL, Jhuang WJ, Dai ZK, Chen WY, Chen YF, Lee AS. The Sodium-Glucose Co-transporter 2 Inhibitor Empagliflozin Attenuates Cardiac Fibrosis and Improves Ventricular Hemodynamics in Hypertensive Heart Failure Rats. Cardiovascular Diabetology 2019 Apr 1;18(1):45.
9. Shiou YL, Lin HT, Ke LY, Wu BN, Shin SJ, Chen CH, Tsai WC, Chu CS, Lee HC*. Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes. J Clin Med 2019, 8(6).
10. Lee HC*, Lin YH. The pathogenic role of very low density lipoprotein on atrial remodeling in the metabolic syndrome. Int J Mol Sci. 2020 Jan 30;21(3). pii: E891.
11. Lin YH, Kang L, Feng WH, Cheng TL, Tsai WC, Huang HT, Lee HC*, Chen CH*. Effects of lipid and lipoprotein on mesenchymal stem cells used in cardiac tissue regeneration. Int J Mol Sci. 2020 July; 21(13), 4770
12. Lee HC*, Shin SJ, Huang JK, Lin MY, Lin YH, Ke LY, Jiang HJ, Tsai WC, Chao MF, Lin YH. The role of postprandial very-low-density lipoprotein in the development of atrial remodeling in metabolic syndrome. Lipids Health Dis 2020, 19 (1), 210.
13. Chou MC+, Lee HC+, Liu YC, Yen PSY, Liu CK, Chen CH, Hsieh TH, Chen SL*. Long-term high-fat diet consumption depletes glial cells and tyrosine hydroxylase–containing neurons in the brain of middle-aged rats. Cells. 2022. 11:295.
14. Huang JK, Lee HC*. Emerging evidence of pathogenic roles of very-low-density lipoprotein (VLDL). Int J Mol Sci. 2022. 23, 4300.
15. Lee HC, Chen CY, Lee SY&, Lee MC, Tsai CY, Chen ST, Li YJ. Exploiting exercise electrocardiography to improve early diagnosis of atrial fibrillation with deep learning neural network. Computers in Biology and Medicine. 2022. 146, 105584.
16. Lee MC, Wang YT, Li YJ, Tsai CY, Chen ST, Jhuang WJ, Chang MC, Chien MY, Lee HC*. QTc interval is associated with atrial fibrilltation in individuals with metabolic syndrome phenotype. International Journal of General Medicine. 2022 Jul 15;15:6189-6198.
17. Lee HC, Akhmedov A, Chen CH. Spotlight on very-low-density lipoprotein as a driver of cardiometabolic disorders: implications for disease progression and mechanistic insights. Frontiers in Cardiovascular Medicine. Invited Review, 2022 Oct 4;9:993633.
18. Lee HC*, Cheng WC, Ma WL, Lin YH, Shin SJ, Lin YH. Association of lipid composition and unsaturated fatty acids of VLDL with atrial remodeling in metabolic syndrome. Sci Rep. 2023 Apr 21;13(1):6575. doi: 10.1038/s41598-023-33757-0.
1. Lee HC, Lin HT, Ke LY, Wei C, Hsiao YL, Chu CS, Lai WT, Shin SJ, Chen CH, Sheu SH, Wu BN. VLDL from metabolic syndrome individuals enhanced lipid accumulation in atria with association of susceptibility to atrial fibrillation. Int J Mol Sci. 2016;17:134.
2. Lee HC, Chiu CC, Chen CC, Huang JW, Lin HT, Hsiao YL, Sheu SH, Hsieh CC. Modulation of potassium channel KCNQ1 transcript in right atrial appendage of patients with postoperative atrial fibrillation. Int J Cardiol. 2016;222, p696-698 (published online: August 4, 2016)
3. Lee HC, Rudy Y, Liang H, Chen CC, Luo CH, Sheu SH, Cui J. Pro-arrhythmogenic effects of the V141M KCNQ1 mutation in short QT syndrome and its potential therapeutic targets - insights from modeling. J Med Biol Eng. 2017 Oct;37(5):780-789. 2017 Jul (Epub)
4. YL Shiou, IC Huang, HT Lin, Lee HC *. High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats. JFMA. 2017 Sep
5. Lee HC, CC Chen, WC Tsai, HT Lin, YL Shiao, SH Sheu, BN Wu, CH Chen, WT Lai. Very-low-density lipoprotein of metabolic syndrome modulates gap junctions and slows cardiac conduction. Sci Rep. 2017 Sep 21;7(1):12050.
6. Lee HC, Lin TH. Air pollution particular matter and atherosclerosis. Acta Cardiol Sin. 2017 Nov; 33(6): 646-647.
7. Lin HT, Shiou YL, Jhuang WJ, Lee HC*. Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats. J. Vis. Exp (JoVE) 2019. (143), e59115, doi:10.3791/59115.
8. Lee HC, Shiou YL, Jhuo SJ, Chang CY, Liu PL, Jhuang WJ, Dai ZK, Chen WY, Chen YF, Lee AS. The Sodium-Glucose Co-transporter 2 Inhibitor Empagliflozin Attenuates Cardiac Fibrosis and Improves Ventricular Hemodynamics in Hypertensive Heart Failure Rats. Cardiovascular Diabetology 2019 Apr 1;18(1):45.
9. Shiou YL, Lin HT, Ke LY, Wu BN, Shin SJ, Chen CH, Tsai WC, Chu CS, Lee HC*. Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes. J Clin Med 2019, 8(6).
10. Lee HC*, Lin YH. The pathogenic role of very low density lipoprotein on atrial remodeling in the metabolic syndrome. Int J Mol Sci. 2020 Jan 30;21(3). pii: E891.
11. Lin YH, Kang L, Feng WH, Cheng TL, Tsai WC, Huang HT, Lee HC*, Chen CH*. Effects of lipid and lipoprotein on mesenchymal stem cells used in cardiac tissue regeneration. Int J Mol Sci. 2020 July; 21(13), 4770
12. Lee HC*, Shin SJ, Huang JK, Lin MY, Lin YH, Ke LY, Jiang HJ, Tsai WC, Chao MF, Lin YH. The role of postprandial very-low-density lipoprotein in the development of atrial remodeling in metabolic syndrome. Lipids Health Dis 2020, 19 (1), 210.
13. Chou MC+, Lee HC+, Liu YC, Yen PSY, Liu CK, Chen CH, Hsieh TH, Chen SL*. Long-term high-fat diet consumption depletes glial cells and tyrosine hydroxylase–containing neurons in the brain of middle-aged rats. Cells. 2022. 11:295.
14. Huang JK, Lee HC*. Emerging evidence of pathogenic roles of very-low-density lipoprotein (VLDL). Int J Mol Sci. 2022. 23, 4300.
15. Lee HC, Chen CY, Lee SY&, Lee MC, Tsai CY, Chen ST, Li YJ. Exploiting exercise electrocardiography to improve early diagnosis of atrial fibrillation with deep learning neural network. Computers in Biology and Medicine. 2022. 146, 105584.
16. Lee MC, Wang YT, Li YJ, Tsai CY, Chen ST, Jhuang WJ, Chang MC, Chien MY, Lee HC*. QTc interval is associated with atrial fibrilltation in individuals with metabolic syndrome phenotype. International Journal of General Medicine. 2022 Jul 15;15:6189-6198.
17. Lee HC, Akhmedov A, Chen CH. Spotlight on very-low-density lipoprotein as a driver of cardiometabolic disorders: implications for disease progression and mechanistic insights. Frontiers in Cardiovascular Medicine. Invited Review, 2022 Oct 4;9:993633.
18. Lee HC*, Cheng WC, Ma WL, Lin YH, Shin SJ, Lin YH. Association of lipid composition and unsaturated fatty acids of VLDL with atrial remodeling in metabolic syndrome. Sci Rep. 2023 Apr 21;13(1):6575. doi: 10.1038/s41598-023-33757-0.
